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罗晓燕 教授
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电话: 021-64252879
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个人简介
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女,博士, 先后毕业于武汉工程大学,获工学学士,南京工业大学,获工学硕士学位,华东理工大学获博士学位,博士期间从事有机不对称催化的合成方法学研究。1993-2003年在武汉工程大学化学制药系工作,主要从事制药合成工艺与工程方面的科研教学工作,2003年至今工作于华东理工大学药学院, 主要从事制药工程设计,有机合成方法学、有机小分子参与的不对称催化方面的研究工作。已在国内外主要刊物上发表论文30余篇,申请中国专利1项,先后主持或参与科研项目9项,其中省部级3项。获得上海市教学成果一等奖 2 项(2017 年,排名第一;2013 年,排名第二)、宝钢优秀教师奖。指导学生参加了六届全国大学生制药工程设计竞赛,获得一等奖 4 项。上海市重点课程和虚拟仿真实验教学项目负责人,主持或参与各级教改项目10余项,主编或参编教材 5 本,发表教学论文 10余篇、服务于教学的实用新型专利 1 项、教学软件著作权 5 项。
1. na yang, fei wu, jiabin gao,luo xiaoyan, weimin yue,synthesis of 3-methyl-2,6-dimethylbicyclo[3.3.1]nonane-exo-2,exo-6-diol, synth. commun, 2009, 39(21), 3934-3939.
2. luo xiaoyan, zhichao jin, pengfei li, jiabin gao, weimin yue, xinmiao liang, jinxing ye, catalytic asymmetric michael addition of α, β-unsaturated aldehydes with ni(ii) complexes of the schiff base of glycine, org. biomol. chem., 2011, 9 (3), 793-801.
3. luo xiaoyan, zhiqiang zhou, feng yu, xin li, xinmiao liang, jinxing ye. asymmetric vinylogous michael reaction of α, β-unsaturated aldehyde with γ-butenolide. chem.lett., 2011, 40(5),518-520.
4. luo xiaoyan, zhiqiang zhou, xin li, xinmiao liang and jinxing ye organocatalytic phospha-michael reaction of α,β-unsaturated aldehydes. rsc adv., 2011, 1, 698-705.
6. zhichao jin, feng yu, xiao wang, huicai huang, luo xiaoyan, xinmiao liang, jinxing ye, a one-pot asymmetric organocatalytic tandem reaction for the synthesis of oxazine derivatives, org. biomol. chem., 2011, 9, 1809-1816.
7. li yi, cao li, luo xiaoyan, deng wei-ping.highly substituted cyclopentenes formation via a stereoselective tandem cdc reaction and cyclization, chin. j. chem. 2012,30, 2834-2838.
8. wang zheng, shi ying, luo xiaoyan, han de-man , deng wei-ping. direct synthesis of pyrroles via 1,3-dipolar cycloaddition of azomethine ylides with ynones. new j. chem., 2013, 37,1742-1745.
9. wang zheng, luo shuai, zhang shoude, yang wu-lin, liu yang-zi, li honglin, luo xiaoyan , deng wei-ping. catalytic asymmetric construction of quaternary a-amino acid-containing pyrrolidines via 1,3-dipolar cycloaddition of azomethine ylides to a-aminoacrylateschem. eur. j., 2013, 19,6739-6745.
10. wei-liang wang, yu-lan feng, wen-qiang gao, luo xiaoyan , wei-ping deng. a highly efficient bf3.et2o-catalysed intramolecular [3 2] cycloaddition for the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles, rsc advances,2013, 3, 1687-1690.
11. zheng-lin wang, hong-liang li , li-shi ge , xing-lan an , zi-gang zhang , luo xiaoyan, john s. fossey, wei-ping deng ,ddq-mediated oxidative coupling: an approach to 2,3-dicyanofuran (thiophene),j. org. chem., 2014, 79 (3), 1156–1165.(highlights in synfacts2014, 10(4), 0374).
12. wang zheng-lin, an xing-lan, ge li-shi, jing-hai jin, luo xiaoyan , deng wei-ping. ddq-mediated oxidation of sp3 c-h bond for the direct synthesis of vicinal tricarbonyl compounds. tetrahedron2014, 70, 3788-3792.
13. li yi, cao li, luo xiaoyan, deng wei-ping. the synthesis of 1, 2-diarylindenes via ddq-mediated dehydrogenative intramolecular cyclization. tetrahedron2014, 70, 5974.
14. ge li-shi, wang zheng-lin, an xing-lan, luo xiaoyan, deng wei-ping ,direct synthesis of polysubstituted 2-aminothiophenes by cu(ii)-catalyzed addition/oxidative cyclization of alkynoates with thioamides, org. biomol. chem. 2014, 12, 8473-8479.
15. luo xiaoyan, wang z-l, jin j-h, an x-l, shen z, deng wei-ping, copper-catalyzed α-aminoxylation of 1,3-dicarbonyl compounds with 2,2,6,6-tetramethylpiperidine-1-oxyl (tempo) via an aerobic oxidative sp3 c-h bond activation, tetrahedron2014, 70, 8226-8230.
16.luo xiaoyan, li-shi ge, xing-lan an, jing-hai jin, yu wang,pei-pei sun and wei-ping deng. regioselective metal-free one-pot synthesis of functionalized 2-aminothiophene derivatives. j. org. chem. 2015,80, 4611-4617.
17.hong-liang li, xing-lan an, li-shi ge, luo xiaoyan, wei-ping deng. catalytic α-hydroxylation of ketones under cubr2 or hbr/dmso systems.tetrahedron2015, 71, 3247-3252.
18. li chun-yan , yang wu-lin , luo xiaoyan, wei-ping deng.diastereodivergent asymmetric michael addition of cyclic azomethine ylides to nitroalkenes: direct approach for the synthesis of 1,7-diazaspiro[4.4]nonane diastereoisomers,chem. eur. j. 2015, 21, 19048–19057.
19. li hong-liang, wang yu, sun pei-pei, luo xiaoyan, shen zhenlu, deng wei-ping.α,β-double electrophilic addition of allene-1,3-dicarboxylic esters for the construction of polysubstituted furans via ki/tbhp promoted oxidative annulation.chem. eur. j. 2016, 22, 9348-9355.
20. wang yu, jiang chen-min, li hong-liang, he fu-sheng, luo xiaoyan, deng wei-ping.regioselective iodine-catalyzed construction of polysubstituted pyrroles from allenes and enamines.j. org. chem.2016, 81, 8653-8658.
21. liu yang-zi, shang shao-jing, yang wu-lin, luo xiaoyan, deng wei-ping.stereoselective synthesis of pyrrolidines containing a 3‑fluoro quaternary stereocenter via copper(i)-catalyzed asymmetric 1,3-dipolar cycloaddition.j. org. chem. 2017, 82(20), 11141-11149.
22. han teng, wang yu, li hong-liang, luo xiaoyan, deng wei-ping.synthesis of polysubstituted 3-aminothiophenes from thioamides and allenes via tandem thio-michael addition/oxidative annulation and 1,2-sulfur migration. j. org. chem.2018, 83, 1538-1542.
23. teng han,luo xiaoyan .thio-michael addition of thioamides and allenes for the selective construction of polysubstituted 2-arylthiophenes via tbai/h2o2 promoted tandem oxidative annulation and 1,2-sulfur migration.org. biomol. chem.2018, 16, 6875-6879.
24. leng jiaying, meng jiang, luo xiaoyan, deng wei-ping. formal [4 1] cycloaddition strategy for the synthesis of dihydrobenzofurans via michael addition of 2-(2-nitrovinyl)-phenols and malonate esters (c1 synthon) and subsequent iodine-catalyzed oxidative annulation.tetrahedron 2018, 74, 6993-6999.
25. jin jing-hai, li xiang-yu, luo xiaoyan, deng wei-ping. enantioselective synthesis of indolo[2,3-b]-dihydrothiopyranones via [3 3] cycloaddition of chiral α,β-unsaturated acylammonium salts.tetrahedron 2018, 74, 6804-6808.
26. wen min, sun pei-pei, luo xiaoyan, deng wei-ping .cu(ii)-catalyzed one-pot synthesis of fully substituted dihydrothiophenes and thiophenes from thioamides and enynones.tetrahedron 2018, 74(31), 4168-4173.
27. wu shu-xiao, gu bo-qi, xu hui, zheng xing, luo xiaoyan, deng wei-ping.organocatalytic asymmetric inverse-electron-demand diels-alder reaction of pyrrolidone-dienes with enals .adv. synth. catal. 2019, 361(18), 4302-4313.
28. mao jia, zhang hao, ding xiang-feng, luo xiaoyan, deng wei-ping .synergistic catalysis for asymmetric [3 2] cycloadditions of 2-indolylmethanols with α,β-unsaturated aldehydes.j. org. chem. 2019, 84(17), 11186-11194.
29. leng jiaying, xu hui, meng jiang, luo xiaoyan, deng wei-ping.transition-metal-free synthesis of polysubstituted pyrrole derivatives via [4 1] annulation of beta-keto acids (c1 synthon) and alpha,beta-unsaturated imines.tetrahedron 2019, 75, 130709
30. chao ye, wu-lin yang, yufei zhai, hua deng, luo xiaoyan, guoyin kai, wei-ping deng. copper(i)-catalyzed asymmetric [3 3] annulation involving aziridines to construct tetrahydro-ß-carbolines. org. chem. front., 2020, 7, 3393-3398.
luo xiaoyankinetic resolution of 2h-azirines via cu(i)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides.org. chem. front., 2020,7, 3247-3252.
32. xu hui, han teng, luo xiaoyan, deng wei-ping. the construction of 3-azabicyclo[3.1.0]hexane backbone by the reaction of allenes with allylamines via tandem aza-michael addition and copper-mediated oxidative carbanion cyclization. chin. j. chem., 2021, 39, 666-670.
33. yang wu-lin, liu tian-tian, ni tao, zhu bin, luo xiaoyan, deng wei-ping. iridium-catalyzed asymmetric cascade allylation/pictet-spengler cyclization reaction for the enantioselective synthesis of 1,3,4-trisubstituted tetrahydroisoquinolines.org. lett., 2021, 23(7), 2790-2796.
34. yang wu-lin, wang yuan-lin, li wen, gu bu-ming, wang si-wen, luo xiaoyan, tian bo-xue, deng wei-ping. diastereo- and enantioselective synthesis of eight-membered heterocycles via an allylation/ring expansion sequence enabled by multiple catalysis. acs catal., 2021, 11, 12557-12564.
研究方向
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有机合成方法学;有机小分子参与的不对称催化;制药工程设计
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